Susceptibilities of Yersinia pestis to Twelve Antimicrobial Agents in China
نویسندگان
چکیده
Objective: Streptomycin is the preferred choice for therapy of plague in China and other countries. However, Yersinia pestis exhibiting plasmid-mediated antimicrobial agent–resistant traits had been reported Madagascar. In this study, we evaluated susceptibility traditional or newer agents used treatment and/or prophylaxis plague. Methods: Following Clinical Laboratory Standards Institute (CLSI) recommendations, 12 was by agar microdilution method 1,012 strains Y. isolated from 1943 to 2017 natural foci China. Results: One clinical isolate (S19960127) found be highly resistant streptomycin, while strain still sensitive 11 antibiotics, that is, ciprofloxacin, ofloxacin, kanamycin, chloramphenicol, ampicillin, ceftriaxone, cefuroxime, trimethoprim-sulfamethoxazole, tetracycline, spectinomycin moxifloxacin. The remaining 1,011 study demonstrated above-mentioned agents. Conclusion: Antimicrobial sensitivity surveillance isolates, including dynamic monitoring streptomycin resistance during various treatments, should carried out routinely.
منابع مشابه
Susceptibilities of Yersinia pestis strains to 12 antimicrobial agents.
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ژورنال
عنوان ژورنال: Zoonoses
سال: 2022
ISSN: ['2737-7474', '2737-7466']
DOI: https://doi.org/10.15212/zoonoses-2022-0018